French · Pronunciation Guide
la ray-POHNS — a throat "r" at the front, a nasal vowel, and a final "s" that is pronounced.
la ré-PONSE, weight on the second syllable. The word ends on a crisp "s" despite the nasal vowel before it — so the vowel is nasal and the consonant is real, with nothing in between.
Listen: la réponse
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Je n'ai pas de réponse.
I don't have an answer.
Listen: Je n'ai pas de réponse.
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"Je n'ai pas de réponse" uses "de" rather than "une" after a negation, which is a firm rule: "je n'ai pas de" replaces any indefinite article in the negative. The "ne" elides before "ai". "Pas de réponse" runs together as three light beats before the final peak.
The nasal gets a real "n" before the "s", producing "ray-PONSS" as an English reader would say it. The "n" is silent as a consonant; only the "s" is real. Learners also voice the "s" into a "z" by analogy with other words. And the negative article rule catches everyone: "je n'ai pas une réponse" is wrong; it must be "pas de".